MGEA5 antibody (AA 756-850)

Catalog No. ABIN721465

This Rabbit Polyclonal antibody specifically detects MGEA5 in WB, ELISA, IF (p), IHC (p), IF (cc) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for MGEA5 antibody (AA 756-850) (ABIN721465)

Target: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGEA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MGEA5 Antibody

Binding Specificity: AA 756-850

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MGEA5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MGEA5

Target: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Alternative Name: MGEA5

Background:

Synonyms: Bunctional protein NCOAT, Glycoside hydrolase O-GlcNAcase, HAT, HEXC, Hexosaminidase C, Histone acetyltransferase, KIAA0679, MEA5, Meningioma expressed antigen 5, Meningioma-expressed antigen 5, MGEA 5, Mgea5, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, NCOAT, NCOAT_HUMAN, Nuclear cytoplasmic O GlcNAcase and acetyltransferase, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase, O-GlcNAcase, OGA, NCOAT_HUMAN.

Background: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008].

Gene ID: 10724

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process