MUC1 antibody

Catalog No. ABIN7529097

The Mouse Monoclonal anti-MUC1 antibody has been validated for FACS. It is suitable to detect MUC1 in samples from Human.

Quick Overview for MUC1 antibody (ABIN7529097)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: C-F2A

Product Details anti-MUC1 Antibody

Purpose: MUC1 Unconjugated Antibody

Characteristics: The clone C-F2A, a mouse monoclonal antibody selectively binds to 500-1000 kD heterodimer transmembrane protein of the mucin family encoded in humans by the MUC1 gene known as MUC1 which also called as CD227. MUC1 is variably expressed on the surfaces of normal and malignant glandular and ductal epithelial cells, some hematopoietic cell lineages including subsets of T cells, B cells, monocytes, and dendritic cells. Due to its overexpression and aberrantly glycosylated in adenocarcinomas and in hematological malignancies, MUC1 (CD227) has been a target for tumor immunotherapeutic studies in mice and in humans.

Purification: Purified

Purity: >95 %

Immunogen: Human Milk Fat Globule Membranes

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: MUC1

Gene ID: 4311

NCBI Accession: NC_00003

UniProt: P08473

Pathways: Negative Regulation of intrinsic apoptotic Signaling