CD7 antibody

Catalog No. ABIN7536989

This Mouse Monoclonal antibody specifically detects CD7 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD7 antibody (ABIN7536989)

Target: CD7

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD7 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: HIT7

Product Details anti-CD7 Antibody

Purpose: AF/LE Purified Anti-Human CD7 Antibody [HIT7]

Purification: Purified

Sterility: 0.2 μm filtered

Endotoxin Level: Low Endotoxin

Isotype: IgG1, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 10⁶ cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Comment:

Matching Isotype Control: (ABIN7469767)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Preservative: Azide free

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Do not freeze.

Expiry Date: 12 months

Target Details for CD7

Target: CD7

Alternative Name: CD7

Background: CD7,T-cell antigen CD7,CD7,GP40,T-cell leukemia antigen,T-cell surface antigen Leu-9,TP41,TP41,CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

Gene ID: 924

UniProt: P09564

Pathways: Cell-Cell Junction Organization