Recombinant CEACAM5 & CD3E (Cibisatamab Biosimilar) antibody
Quick Overview for Recombinant CEACAM5 & CD3E (Cibisatamab Biosimilar) antibody (ABIN7538087)
Target
Antibody Type
Reactivity
Host
Clonality
Application
Grade
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Expression System
- Mammalian cells
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Purpose
- Cibisatamab Biosimilar – Anti-CEACAM5 & CD3E mAb - Research Grade
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Characteristics
- Antibody Type: Bispecific mAb with Domain Crossover
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Purification
- Recombinant antibody expressed in mammalien cells and purified.
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Purity
- > 85%
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Isotype
- IgG1 kappa, IgG1 lambda
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Restrictions
- For Research Use only
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Buffer
- PBS buffer PH7.5
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Storage
- -80 °C
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Storage Comment
- store at -80°C
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- CEACAM5 & CD3E (Cibisatamab Biosimilar)
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Target Type
- Biosimilar
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Background
- Cibisatamab (CEA-TCB), a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab (CEA-TCB) triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab (CEA-TCB) can be used for colorectal cancer research.
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CAS-No
- 1855925-27-7
Target
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