Dystrophin antibody (C-Term)

Catalog No. ABIN7538879

The Mouse Monoclonal anti-Dystrophin antibody has been validated for IHC. It is suitable to detect Dystrophin in samples from Human.

Quick Overview for Dystrophin antibody (C-Term) (ABIN7538879)

Target: Dystrophin (DMD)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Dystrophin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: Dy8-6C5

Product Details anti-Dystrophin Antibody

Binding Specificity: C-Term

Purpose: Lyophilized Mouse Monoclonal Antibody Dystrophin (C-terminus)

Specificity: Reacts strongly with the carboxy terminus (between amino acids 3669 and 3685) of human dystrophin. Also crosssreacts strongly with skeletal, cardiac and smooth muscle dystrophin from normal mouse, rat, rabbit, dog, chicken and hamster. No crossreactivity with mdx mouse tissue. Crossreacts very weakly with pig dystrophin.

Characteristics: This product is intended for the qualitative identification by light microscopy of Dystrophin (C-terminus) by immunohistochemistry.

Purification: Tissue culture supernatant

Immunogen: Synthetic polypeptide consisting of the last 17 amino acids at the carboxy terminus of the human dystrophin sequence.

Isotype: IgG1

Application Details

Application Notes: Immunohistochemical (IHC) staining techniques allow for the visualization of antigens via the sequential application of a specific antibody to the antigen (primary antibody), a secondary antibody to the primary antibody and an enzyme complex with a chromogenic substrate with interposed washing steps. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and coverslipped. Results are interpreted using a light microscope.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label.

Buffer: This product is a lyophilized tissue culture supernatant containing sodium azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8 °C. Do not freeze. Return to 2-8 °C immediately after use. Do not use after expiration date indicated on the vial label. Storage conditions other than those specified above must be verified by the user.

Expiry Date: 12 months

Target Details for Dystrophin

Target: Dystrophin (DMD)

Alternative Name: Dystrophin

Pathways: Skeletal Muscle Fiber Development