Topoisomerase II alpha antibody (C-Term)

Catalog No. ABIN7538938

This Mouse Monoclonal antibody specifically detects Topoisomerase II alpha in IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Topoisomerase II alpha antibody (C-Term) (ABIN7538938)

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Topoisomerase II alpha antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3F6

Product Details anti-Topoisomerase II alpha Antibody

Binding Specificity: C-Term

Purpose: Liquid Mouse Monoclonal Antibody Topoisomerase II Alpha

Specificity: Human topoisomerase II alpha.

Characteristics: This product is intended for the qualitative identification by light microscopy of human topoisomerase II alpha in paraffin sections.

Purification: Tissue culture supernatant

Immunogen: Prokaryotic recombinant protein corresponding to the C-terminal region of the topoisomerase II alpha molecule.

Isotype: IgG1

Application Details

Application Notes: Immunohistochemical (IHC) staining techniques allow for the visualization of antigens via the sequential application of a specific antibody to the antigen (primary antibody), a secondary antibody to the primary antibody and an enzyme complex with a chromogenic substrate with interposed washing steps. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and coverslipped. Results are interpreted using a light microscope.

Comment:

Is recommended for the assessment of topoisomerase II alpha protein expression in normal and neoplastic tissues.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The product is a liquid tissue culture supernatant containing sodium azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8 °C. Do not freeze. Return to 2-8 °C immediately after use. Do not use after expiration date indicated on the vial label. Storage conditions other than those specified above must be verified by the user.

Expiry Date: 12 months

Target Details for Topoisomerase II alpha

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Alternative Name: Topoisomerase II Alpha

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases