IL3RA antibody

Catalog No. ABIN7539423

This anti-IL3RA antibody is a Mouse Monoclonal antibody detecting IL3RA in FACS. Suitable for Human.

Quick Overview for IL3RA antibody (ABIN7539423)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL3RA antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: HI12H7

Product Details anti-IL3RA Antibody

Purpose: CD123 Unconjugated Antibody

Characteristics: The clone HI12H7, a mouse monoclonal antibody, specifically targets the 70 kDa transmembrane α chain of the IL3 receptor, also known as CD123. This receptor is prominently expressed in various cells within the hematopoietic system, including hematopoietic progenitor cells, monocytes, and B-lymphocytes. CD123 plays a crucial role in regulating the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Notably, elevated levels of CD123 expression are frequently observed in a range of hematolymphoid neoplasms. These include acute myeloid leukemia, blastic plasmacytoid dendritic cell neoplasm, acute lymphoblastic leukemia, hairy cell leukemia, systemic mastocytosis, and certain types of B cells.

Purification: Purified

Purity: >95 %

Immunogen: Human IL3Ralpha transfected COS cells

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: CD123

Gene ID: 3815

NCBI Accession: NP_000213, NP_001087241

UniProt: P10721

Pathways: JAK-STAT Signaling