CD40 Ligand antibody

Catalog No. ABIN7539620

The Mouse Monoclonal anti-CD40 Ligand antibody (Clone 24-31) (ABIN7539620) specifically detects CD40 Ligand in FACS. The antibody is reactive with Human samples.

Quick Overview for CD40 Ligand antibody (ABIN7539620)

Target: CD40 Ligand (CD40LG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 Ligand antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 24-31

Product Details anti-CD40 Ligand Antibody

Purpose: AF/LE Purified Anti-Human CD154 Antibody [24-31]

Specificity: Human

Purification: Protein A/G Purified

Endotoxin Level: Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.

Immunogen: Recombinant Human CD154 protein

Isotype: IgG1, kappa

Application Details

Application Notes: FCM:2 μg/mL(1x10^5-5x10^5 cells)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS.

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Target Details for CD40 Ligand

Target: CD40 Ligand (CD40LG)

Alternative Name: CD154

Background: CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Gene ID: 959

UniProt: P29965

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints