Cyclin B3 antibody (AA 142-363)

Catalog No. ABIN7539697

The Mouse Monoclonal anti-Cyclin B3 antibody has been validated for ELISA and FACS. It is suitable to detect Cyclin B3 in samples from Human.

Quick Overview for Cyclin B3 antibody (AA 142-363) (ABIN7539697)

Target: Cyclin B3 (CCNB3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin B3 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 4B4D8

Product Details anti-Cyclin B3 Antibody

Binding Specificity: AA 142-363

Purpose: CCNB3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CCNB3 (AA: 142-363) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Cyclin B3

Target: Cyclin B3 (CCNB3)

Alternative Name: CCNB3

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 158 kDa

Gene ID: 85417

UniProt: Q8WWL7

Pathways: Cell Division Cycle, Chromatin Binding