RAD23B antibody

Catalog No. ABIN7539777

This Mouse Monoclonal antibody specifically detects RAD23B in WB, IHC, ICC and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for RAD23B antibody (ABIN7539777)

Target: RAD23B (RAD23 Homolog B (RAD23B))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAD23B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 6D2B3

Product Details anti-RAD23B Antibody

Purpose: RAD23B Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RAD23B expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

FCM: 1/200 - 1/400

ICC: 1/100 - 1/400

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RAD23B

Target: RAD23B (RAD23 Homolog B (RAD23B))

Alternative Name: RAD23B

Background: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 43.2 kDa

Gene ID: 5887

UniProt: P54727

Pathways: DNA Damage Repair