PAX5 antibody

Catalog No. ABIN7540473

The Rat Monoclonal anti-PAX5 antibody is suitable to detect PAX5 in samples from Human and Mouse. It has been validated for WB, IHC (p), ICC, IP and ICFC.

Quick Overview for PAX5 antibody (ABIN7540473)

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP), Intracellular Flow Cytometry (ICFC)

Clone: 1H9

Product Details anti-PAX5 Antibody

Purpose: Anti-PAX5 Purified

Characteristics: The rat monoclonal antibody 1H9 recognizes transcription factor PAX5 (intracellular antigen).

Purification: Purified by protein-A affinity chromatography.

Immunogen: GST-tagged recombinant mouse PAX5

Isotype: IgG2a, kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background:

NCBI Full Gene Name: paired box 5

Description: PAX5 is a transcription factor expressed in hematopoietic cells of B cell line, and partially also in the nervous system. It is important for B cell development and differentiation, but its expression must finally be be suppressed to enable plasma cell maturation. PAX5 thus affects the balance between B cell proliferation and antibody production. Its overexpression is associated with many lymphomas.

Other names: ALL3, BSAP

Gene name: PAX5

Gene ID: 5079

UniProt: Q02548