Human Adenovirus type 2 E1A (HAdV-2 E1A) antibody

Catalog No. ABIN7540660

Supplier Product No.: mob355-01

The Mouse Monoclonal anti-Human Adenovirus type 2 E1A antibody (Clone M58-M73) (ABIN7540660) specifically detects Human Adenovirus type 2 E1A in IHC. The antibody is reactive with Adenovirus samples.

Quick Overview for Human Adenovirus type 2 E1A (HAdV-2 E1A) antibody (ABIN7540660)

Target: Human Adenovirus type 2 E1A (HAdV-2 E1A)

Reactivity: Adenovirus

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Clone: M58-M73

Product Details

Supplier Product No.: mob355-01

Supplier: Rockland

Purpose: Adenovirus Monoclonal Antibody

Cross-Reactivity (Details): This antibody reacts with adenovirus.

Purification: The antibody is supplied as a purified immunoglobulin.

Immunogen: Anti-Adenovirus Monoclonal Antibody was produced in BALB/C mice by repeated immunizations with adenovirus.

Isotype: IgG2a kappa

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:25-1:50

Comment:

Anti-Adenovirus (MOUSE) Monoclonal Antibody was tested in IHC-P with positive control adenovirus infected tissues. Cellular Localization: Nuclear. The user is advised to validate the use of the products with their tissue specimens prepared and handled in accordance with their laboratory practices. Consult references (Kiernan, 1981: Sheehan & Hrapchak, 1980) for further details on specimen preparation.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. This antibody is suitable for use until the expiration date when stored at 2-8°C. Do not use product after the expiration date printed on vial. If reagents are stored under conditions other than those specified here, they must be verified by the user. Diluted reagents should be used promptly. Unused portions of antibody preparation should be discarded after one day. The presence of precipitate or an unusual odor indicates that the antibody is deteriorating and should not be used.

Target Details

Target: Human Adenovirus type 2 E1A (HAdV-2 E1A)

Alternative Name: E1A

Target Type: Viral Protein

Background: Adenoviruses, DNA virus,The adenovirus early gene product E1A is a potent stimulator of cellular proliferation, which when overexpressed can overcome the growth-inhibitory effects of TGF-β. The E1A region encodes a series of related proteins (35-46 kDa) with multifunctional capabilities and forms a specific complex with the retinoblastoma tumor suppressor gene product. The E1A and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region.