Recombinant IL-4 antibody

Catalog No. ABIN7542997

This anti-IL-4 antibody is a Rabbit Chimeric antibody detecting IL-4 in FACS and BR. Suitable for Rat.

Quick Overview for Recombinant IL-4 antibody (ABIN7542997)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Antibody Type: Recombinant Antibody

Reactivity: Rat

Host: Rabbit

Clonality: Chimeric

Conjugate: This IL-4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: OX-81

Product Details anti-IL-4 Antibody

Purpose: Anti-IL-4 [OX-81], Rabbit IgG, kappa

Specificity: OX-81 binds specifically to IL-4. IL-4 is a globular signalling protein which is involved in the stimilation of activated B and T cell proliferation and the differentiation of B cells into plasma cells. IL-4 also regulates B cell class switching to IgE, upregulates MHC class II expression and plays a role in the inflammation response and wound repair.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: OX-81 was prepared by immunizing BALB/c mice with full-length IL-4.

Isotype: IgG kappa

Application Details

Application Notes: OX-81 can be used to neutralise the effects produced by IL-4 and for FC studies.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4

Background: BSF-1, OX81, MRC OX-81, MRC OX81, interleukin 4, interleukin-4, IL4, B-cell IGG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, BSF1, Lymphocyte stimulatory factor 1

UniProt: P20096

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation