Recombinant CD172b / SIRP beta antibody

Catalog No. ABIN7543024

The Rabbit Chimeric anti-CD172b / SIRP beta antibody (Clone OX-130) (ABIN7543024) specifically detects CD172b / SIRP beta in ELISA, FACS and SPR. The antibody is reactive with Human samples.

Quick Overview for Recombinant CD172b / SIRP beta antibody (ABIN7543024)

Target: CD172b / SIRP beta

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: Un-conjugated

Application: ELISA, Flow Cytometry (FACS), Surface Plasmon Resonance (SPR)

Clone: OX-130

Product Details

Purpose: Anti-CD172b / SIRPB [OX-130], Rabbit IgG, kappa

Specificity:

This antibody recognizes both common alleles of the human activating SIRPβ1 receptor, does not recognize SIRPγ, but cross-reacts with one of the common alleles of the inhibitory human SIRPα receptor.

Application Notes original Clone: This antibody binds both common alleles of the human activating SIRPβ1 receptor, but ELISA and surface plasmon resonance results have shown that it reacts with one of the two common alleles of SIRPα, potentially yielding different outcomes when this antibody is used in assays from different individuals.

Characteristics: This chimeric rabbit antibody was made using the variable domain sequences of the original mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogen: Recombinant SIRPbeta1 was purified by nickel affinity chromatography and used to immunize mice.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Mouse

OriginalFormat: IgG2b

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details

Target: CD172b / SIRP beta

Background: SIRP-beta-1, Signal-regulatory protein beta-1, CD172 antigen-like family member B

UniProt: O00241