Recombinant DLL4 antibody

Catalog No. ABIN7543201

This anti-DLL4 antibody is a Mouse Monoclonal antibody detecting DLL4 in ELISA, IHC, IF and BP. Suitable for Human.

Quick Overview for Recombinant DLL4 antibody (ABIN7543201)

Target: DLL4 (delta-Like 4 (DLL4))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Blocking Peptide (BP)

Clone: 61B

Product Details anti-DLL4 Antibody

Purpose: Anti-DLL4 [61B], Mouse IgG2a, kappa

Specificity: This antibody is specific for the EGF-like 3 domain of Dll4.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with soluble human Dll4-His protein.

Isotype: IgG2a kappa

Application Details

Application Notes: U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015, pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015, pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015, pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4

Background: Delta-like protein 4, Drosophila Delta homolog 4, Delta4

UniProt: Q9NR61

Pathways: Notch Signaling