Recombinant PSMA antibody

Catalog No. ABIN7543286

This Rabbit Chimeric antibody specifically detects PSMA in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Recombinant PSMA antibody (ABIN7543286)

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This PSMA antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 11d1e5E10

Product Details anti-PSMA Antibody

Purpose: Anti-PSMA [11d1e5E10], Rabbit IgG, kappa

Specificity: This antibody binds an epitope between amino acids 370 and 750 of the human PSMA. Prostate-specific membrane antigen (PSMA) is a type II integral membrane glycoprotein belonging to the M28 peptidase family. It acts as a glutamate carboxypeptidase on different alternative substrate. It is highly expressed in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with a HIS tagged human PSMA fragment (amino acids between 307 to 750).

Isotype: IgG kappa

Application Details

Application Notes: The binding characterization of this antibody was done using ELISA. This antibody is also recommended for the detection of PSMA using immunohistochemistry (CN112480260).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for PSMA

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Alternative Name: PSMA

Background: PSM, FOLH1, FOLH, FGCP, GCPII, mGCP, NAALAD1, GIG27, Prostate specific membrane antigen, Glutamate carboxypeptidase 2, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Prostate-specific membrane antigen, Pteroylpoly-gamma-glutamate carboxypeptidase

UniProt: Q04609