Recombinant Desmin antibody
Quick Overview for Recombinant Desmin antibody (ABIN7543360)
Target
See all Desmin (DES) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Desmin [14G1C12], Rabbit IgG, kappa
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Specificity
- The antibody is specific for Desim. Desim is a muscle-specific type III intermediate filament essential for proper muscular structure and function. It plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity.
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Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing BALB/c mice with recombinant DESMIN.
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Isotype
- IgG kappa
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Application Notes
- This antibody was used for immunohistochemistry on esophageal, leiomyoma and rhabdomyosarcoma tissue (CN109485724).
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Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Desmin (DES)
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Alternative Name
- Desmin
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UniProt
- P17661
Target
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