Recombinant CHRNB2 antibody

Catalog No. ABIN7543387

This anti-CHRNB2 antibody is a Mouse Monoclonal antibody detecting CHRNB2 in ELISA. Suitable for Human.

Quick Overview for Recombinant CHRNB2 antibody (ABIN7543387)

Target: CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHRNB2 antibody is un-conjugated

Application: ELISA

Clone: 12H2

Product Details anti-CHRNB2 Antibody

Purpose: Anti-Nicotinic acetylcholine alpha4 beta 2 receptor [12H2], Mouse IgG1, kappa

Specificity: This antibody recognizes human α4β2 receptor protein. The AChR responds by an extensive change in conformation after binding acetylcholine, that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing female BALB/c mice with human alpha4beta2 receptor protein purified in n-dodecyl-beta-D-maltopyranoside (DDM).

Isotype: IgG1 kappa

Application Details

Application Notes: The binding characterization of this antibody to human α4β2 nicotinic receptor was done using ELISA.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CHRNB2

Target: CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))

Alternative Name: Nicotinic acetylcholine alpha4 beta 2 receptor

Background: CHRNB2, Nicotinic acetylcholine α4β2 receptor, Neuronal acetylcholine receptor subunit beta-2, human α4β2 nicotinic receptor, AChR

UniProt: P17787

Pathways: Sensory Perception of Sound, Feeding Behaviour