Recombinant CHRNB2 antibody
Quick Overview for Recombinant CHRNB2 antibody (ABIN7543388)
Target
See all CHRNB2 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Nicotinic acetylcholine alpha4 beta 2 receptor [12H2], Rabbit IgG, kappa
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Specificity
- This antibody recognizes human α4β2 receptor protein. The AChR responds by an extensive change in conformation after binding acetylcholine, that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.
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Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing female BALB/c mice with human alpha4beta2 receptor protein purified in n-dodecyl-beta-D-maltopyranoside (DDM).
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Isotype
- IgG kappa
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Application Notes
- The binding characterization of this antibody to human α4β2 nicotinic receptor was done using ELISA.
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Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))
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Alternative Name
- Nicotinic acetylcholine alpha4 beta 2 receptor
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Background
- CHRNB2, Nicotinic acetylcholine α4β2 receptor, Neuronal acetylcholine receptor subunit beta-2, human α4β2 nicotinic receptor, AChR
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UniProt
- P17787
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Pathways
- Sensory Perception of Sound, Feeding Behaviour
Target
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