Recombinant Ferritin antibody

Catalog No. ABIN7543449

The Rabbit Chimeric anti-Ferritin antibody is suitable to detect Ferritin in samples from Human. It has been validated for ELISA.

Quick Overview for Recombinant Ferritin antibody (ABIN7543449)

Target: Ferritin (FE)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This Ferritin antibody is un-conjugated

Application: ELISA

Clone: F11

Product Details anti-Ferritin Antibody

Purpose: Anti-Ferritin [F11 (HSF102)], Rabbit IgG, kappa

Specificity:

This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.

Application Notes original Clone: The binding characterization of this antibody towards human spleen ferritin was done using ELISA. This antibody was also reported to show binding affinity for protein A. Binding of this antibody to ferritin causes antigen-induced conformational changes in the antibody and reduces its affinity for protein A (PMID: 9776583).

Characteristics: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Mouse

OriginalFormat: IgG2a

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for Ferritin

Target: Ferritin (FE)

Alternative Name: Ferritin

Background: FTMT, FTL, FTH1, Ferritin mitochondrial, B8

UniProt: Q8N4E7

Pathways: Transition Metal Ion Homeostasis