Stabilin 1 antibody (AA 1201-1400)

Catalog No. ABIN722395

This Rabbit Polyclonal antibody specifically detects Stabilin 1 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for Stabilin 1 antibody (AA 1201-1400) (ABIN722395)

Target: Stabilin 1 (STAB1)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stabilin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Stabilin 1 Antibody

Binding Specificity: AA 1201-1400

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human stabilin1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Stabilin 1

Target: Stabilin 1 (STAB1)

Alternative Name: stabilin1

Background:

Synonyms: CLEVER 1, Common lymphatic endothelial and vascular endothelial receptor 1, Fasciclin EGF like laminin type EGF like and link domain containing scavenger receptor 1, fasciclin egf-like, FEEL 1, FELE 1, FEX1, KIAA0246, MS 1 antigen, STAB1, STAB-1, STAB 1, STAB1_HUMAN.

Background: Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes.

Gene ID: 23166