Stabilin 1 antibody (PE-Cy7)

Catalog No. ABIN722408

The Rabbit Polyclonal anti-Stabilin 1 antibody has been validated for WB. It is suitable to detect Stabilin 1 in samples from Human, Mouse, Rat and Cow.

Quick Overview for Stabilin 1 antibody (PE-Cy7) (ABIN722408)

Target: Stabilin 1 (STAB1)

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stabilin 1 antibody is conjugated to PE-Cy7

Application: Western Blotting (WB)

Product Details anti-Stabilin 1 Antibody (PE-Cy7)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human stabilin1

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Stabilin 1

Target: Stabilin 1 (STAB1)

Alternative Name: Stabilin1

Background:

Synonyms: CLEVER 1, Common lymphatic endothelial and vascular endothelial receptor 1, Fasciclin EGF like laminin type EGF like and link domain containing scavenger receptor 1, fasciclin egf-like, FEEL 1, FELE 1, FEX1, KIAA0246, MS 1 antigen, STAB1, STAB-1, STAB 1, STAB1_HUMAN.

Background: Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes.

Gene ID: 23166