Tyrosine Hydroxylase antibody (AA 101-165)

Catalog No. ABIN723635

The Rabbit Polyclonal anti-Tyrosine Hydroxylase antibody has been validated for WB, ELISA, IHC (p), IHC (fro), IF (cc) and IF (p). It is suitable to detect Tyrosine Hydroxylase in samples from Human, Rat and Mouse. There are 5+ publications available.

Quick Overview for Tyrosine Hydroxylase antibody (AA 101-165) (ABIN723635)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Tyrosine Hydroxylase Antibody

Binding Specificity: AA 101-165

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Tyrosine Hydroxylase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Tyrosine Hydroxylase antibody (ABIN723635)

Shu, Huang, Zeng, He, Luo, Liu, Li, Xu: "Connexin 43 is involved in the sympathetic atrial fibrillation in canine and canine atrial myocytes." in: Anatolian journal of cardiology, Vol. 18, Issue 1, pp. 3-9, (2019) (PubMed).

Häfner, Bohnenpoll, Rudat, Schultheiss, Kispert: "Fgfr2 is required for the expansion of the early adrenocortical primordium." in: Molecular and cellular endocrinology, Vol. 413, pp. 168-77, (2015) (PubMed).

Yu, Liao, Liu, Chen, Feng, Fu: "Overexpression of lactate dehydrogenase-A in human intrahepatic cholangiocarcinoma: its implication for treatment." in: World journal of surgical oncology, Vol. 12, pp. 78, (2014) (PubMed).

Li, Shang, Shu, Zhang, Ji, Sun, Li, Xie: "gga-miR-375 plays a key role in tumorigenesis post subgroup J avian leukosis virus infection." in: PLoS ONE, Vol. 9, Issue 4, pp. e90878, (2014) (PubMed).

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine Hydroxylase

Background:

Synonyms: TYH, DYT14, DYT5b, Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH

Background: Neuronal Marker Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

Gene ID: 7054

UniProt: P07101

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour