BTG2 antibody (AA 31-110) (HRP)

Catalog No. ABIN723914

The Rabbit Polyclonal anti-BTG2 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect BTG2 in samples from Human and Mouse.

Quick Overview for BTG2 antibody (AA 31-110) (HRP) (ABIN723914)

Target: BTG2 (BTG Family, Member 2 (BTG2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTG2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BTG2 Antibody (HRP)

Binding Specificity: AA 31-110

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BTG2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BTG2

Target: BTG2 (BTG Family, Member 2 (BTG2))

Alternative Name: BTG2

Background:

Synonyms: BTG2_HUMAN, Protein BTG2, BTG family member 2, NGF-inducible anti-prolerative protein PC3, pheochromacytoma cell-3, nerve growth factor-inducible anti-prolerative, B-cell translocation gene 2, BTG2, TIS21, PC3, TIS21.

Background: BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1(referenced from Entrez Gene). BTG2 expression is induced in vivo during neurogenesis, and the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor (NGF), suggesting that BTG2 is functionally significant during the neuronal differentiation process (PMID: 12360398).

Gene ID: 7832

UniProt: P78543

Pathways: MAPK Signaling