Caspase 13 + 4 antibody (Cy5.5)

Catalog No. ABIN724225

This Rabbit Polyclonal antibody specifically detects Caspase 13 + 4 in WB, IF (cc) and IF (p). It exhibits reactivity toward Cow.

Quick Overview for Caspase 13 + 4 antibody (Cy5.5) (ABIN724225)

Target: Caspase 13 + 4

Reactivity: Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details

Predicted Reactivity: Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from bovine Caspase-13

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Caspase 13 + 4

Background:

Synonyms: CASP-13, CASP4, Caspase 13 subunit 1, Caspase 13 subunit 2, Caspase 4, Caspase 4 subunit 1, Caspase 4, apoptosis related cysteine, CASPD_BOVIN, Caspase-13, Evolutionary related interleukin-1-beta-converting enzyme, ERICE.

Background: Caspase-13 (also designated Evolutionarily related interleukin-1beta converting enzyme , ERICE) involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. [subunit] Heterodimer of a small and a large subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8. Mainly expressed in peripheral blood lymphocytes, spleen and placenta. Belongs to peptidase family C14.