Caspase 13 + 4 antibody (HRP)

Catalog No. ABIN724229

The Rabbit Polyclonal anti-Caspase 13 + 4 antibody is suitable to detect Caspase 13 + 4 in samples from Cow. It has been validated for WB, ELISA, IHC (fro) and IHC (p).

Quick Overview for Caspase 13 + 4 antibody (HRP) (ABIN724229)

Target: Caspase 13 + 4

Reactivity: Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Predicted Reactivity: Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from bovine Caspase-13

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Caspase 13 + 4

Background:

Synonyms: CASP-13, CASP4, Caspase 13 subunit 1, Caspase 13 subunit 2, Caspase 4, Caspase 4 subunit 1, Caspase 4, apoptosis related cysteine, CASPD_BOVIN, Caspase-13, Evolutionary related interleukin-1-beta-converting enzyme, ERICE.

Background: Caspase-13 (also designated Evolutionarily related interleukin-1beta converting enzyme , ERICE) involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. [subunit] Heterodimer of a small and a large subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8. Mainly expressed in peripheral blood lymphocytes, spleen and placenta. Belongs to peptidase family C14.