CRP antibody (FITC)

Catalog No. ABIN7565981

The Goat Polyclonal anti-CRP antibody has been validated for WB, DB, FLISA and FM. It is suitable to detect CRP in samples from Human.

Quick Overview for CRP antibody (FITC) (ABIN7565981)

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CRP antibody is conjugated to FITC

Application: Western Blotting (WB), Dot Blot (DB), FLISA, Fluorescence Microscopy (FM)

Product Details anti-CRP Antibody (FITC)

Purpose: CRP Antibody Fluorescein Conjugated

Cross-Reactivity (Details): Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-fluorescein, anti-Goat Serum, purified and partially purified Human CRP.

Characteristics: Synonyms: goat anti-CRP fluorescein conjugated Antibody, goat anti-CRP FITC conjugated Antibody, C reactive protein pentraxin related antibody, CRP antibody, MGC88244 antibody, PTX 1 antibody, PTX1 antibody

Purification: This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.

Sterility: Sterile filtered

Immunogen:

Immunogen: Human CRP (Capsular Reactive Protein)

Immunogen Type: Native Protein

Labeling Ratio: 2.2

Application Details

Application Notes: Application Note: Anti-CRP FITC conjugated antibody has been tested by dot blot and is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing various commercial platforms. Western Blot Dilution: User Optimized FLISA Dilution: User Optimized IF Microscopy Dilution: User Optimized Other: User Optimized

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Preservative: 0.01 % (w/v) Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Expiry Date: 12 months

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Alternative Name: CRP

Background: Background: CRP (C-Reactive Protein) belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. CRP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Diseases associated with CRP include Acute Pancreatitis and Appendicitis. Anti-CRP Antibody is ideal for researchers interested in cAMP Dependent PKA, IL6 signaling, calcium ion binding, and cholesterol binding.

Gene ID: 1401

NCBI Accession: NP_000558

UniProt: P02741

Pathways: Carbohydrate Homeostasis