Resistin antibody
Quick Overview for Resistin antibody (ABIN7566445)
Target
See all Resistin (RETN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- anti-Resistin (mouse), mAb (MRES18)
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Characteristics
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Monoclonal antibody. Recognizes mouse resistin. Does not cross-react with human resistin. Applications: ELISA. Isotype: Mouse IgG1kappa. Clone: MRES18. Liquid. In PBS containing 0.02 % sodium azide. The adipokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMα/FIZZ 1 and RELMβ/FIZZ 2) of FIZZ (found in inflammatory zone) that are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
The adipokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) that are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
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Purification
- Puified
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Purity
- >95 % (SDS-PAGE)
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Immunogen
- Recombinant mouse resistin.
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Isotype
- IgG1 kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- In PBS containing 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
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+4°C
Stable for at least 1 year after receipt when stored at -20°C.
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- Resistin (RETN)
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Alternative Name
- Resistin
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UniProt
- Q99P87
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
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