2B4 antibody (PE,Cy5)

Catalog No. ABIN7566585

The PE,Cy5-conjugated Mouse Monoclonal anti-2B4 antibody (Clone C1-7) (ABIN7566585) specifically detects 2B4 in FACS. The antibody is reactive with Human samples.

Quick Overview for 2B4 antibody (PE,Cy5) (ABIN7566585)

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This 2B4 antibody is conjugated to PE,Cy5

Application: Flow Cytometry (FACS)

Clone: C1-7

Product Details anti-2B4 Antibody (PE,Cy5)

Purpose: PE/Cyanine5 Anti-Human CD244 Antibody[C1.7]

Isotype: IgG1, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Alternative Name: CD244

Background: 2B4,SLAMF4,CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.

Gene ID: 51744

UniProt: Q9BZW8