CD80 antibody (Elab Fluor®Violet 610)

Catalog No. ABIN7566681

The Armenian Hamster Monoclonal anti-CD80 antibody has been validated for FACS. It is suitable to detect CD80 in samples from Human.

Quick Overview for CD80 antibody (Elab Fluor®Violet 610) (ABIN7566681)

Target: CD80

Reactivity: Human

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This CD80 antibody is conjugated to Elab Fluor®Violet 610

Application: Flow Cytometry (FACS)

Clone: 16-10A1

Product Details anti-CD80 Antibody (Elab Fluor®Violet 610)

Purpose: Elab Fluor®Violet 610 Anti-Mouse CD80 Antibody[16-10A1]

Isotype: IgG

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: E-AB-F09852T

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for CD80

Target: CD80

Alternative Name: CD80

Background: Activation B7-1 antigen,B7,Cd80,T-lymphocyte activation antigen CD80,CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Gene ID: 12519

UniProt: Q00609

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints