PD-1 antibody (Elab Fluor®700)

Catalog No. ABIN7566873

The Elab Fluor®700-conjugated Rat Monoclonal anti-PD-1 antibody (Clone 29F-1A12) (ABIN7566873) specifically detects PD-1 in FACS. The antibody is reactive with Mouse samples.

Quick Overview for PD-1 antibody (Elab Fluor®700) (ABIN7566873)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This PD-1 antibody is conjugated to Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: 29F-1A12

Product Details anti-PD-1 Antibody (Elab Fluor®700)

Purpose: Elab Fluor®700 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]

Isotype: IgG

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: E-AB-F09832M1

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: CD279/PD-1

Background: Programmed Death-1,PD-1,CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Gene ID: 18566

UniProt: Q02242

Pathways: Cancer Immune Checkpoints