LAMP1 antibody (Elab Fluor®700)

Catalog No. ABIN7566894

The Mouse Monoclonal anti-LAMP1 antibody has been validated for FACS. It is suitable to detect LAMP1 in samples from Human.

Quick Overview for LAMP1 antibody (Elab Fluor®700) (ABIN7566894)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAMP1 antibody is conjugated to Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: H4A3

Product Details anti-LAMP1 Antibody (Elab Fluor®700)

Purpose: Elab Fluor®700 Anti-Human CD107a/LAMP-1 Antibody[H4A3]

Isotype: IgG

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: E-AB-F09792M1

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: CD107a/LAMP-1

Background: LAMP-1, LGP-120,Lysosome-Associated Membrane Protein 1,CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

Gene ID: 3916

UniProt: P11279

Pathways: Autophagy