Sca-1/Ly-6A/E antibody (Elab Fluor®700)

Catalog No. ABIN7566926

The Rat Monoclonal anti-Sca-1/Ly-6A/E antibody has been validated for FACS. It is suitable to detect Sca-1/Ly-6A/E in samples from Mouse.

Quick Overview for Sca-1/Ly-6A/E antibody (Elab Fluor®700) (ABIN7566926)

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Sca-1/Ly-6A/E antibody is conjugated to Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: D7

Product Details anti-Sca-1/Ly-6A/E Antibody (Elab Fluor®700)

Purpose: Elab Fluor®700 Anti-Mouse Ly6A/E(Sca-1) Antibody[D7]

Isotype: IgG2a, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: E-AB-F09832M1

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for Sca-1/Ly-6A/E

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Alternative Name: Ly6A/E(Sca-1)

Background: Ly-6A.2/Ly-6E.1,Ly6,Ly6a,SCA-1,TAP,Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Gene ID: 110454

UniProt: P05533

Pathways: Sensory Perception of Sound, Activated T Cell Proliferation