Sca-1/Ly-6A/E antibody (Elab Fluor®700)

Catalog No. ABIN7566928

This Rat Monoclonal antibody specifically detects Sca-1/Ly-6A/E in FACS. It exhibits reactivity toward Mouse.

Quick Overview for Sca-1/Ly-6A/E antibody (Elab Fluor®700) (ABIN7566928)

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Sca-1/Ly-6A/E antibody is conjugated to Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: D7

Product Details anti-Sca-1/Ly-6A/E Antibody (Elab Fluor®700)

Purpose: Elab Fluor®700 Anti-Mouse Ly6A/E(Sca-1) Antibody[D7]

Isotype: IgG2a, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Comment:

Matching Isotype Control: E-AB-F09833M1

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for Sca-1/Ly-6A/E

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Alternative Name: Ly6A/E(Sca-1)

Background: Ly-6A.2/Ly-6E.1,Ly6,Ly6a,SCA-1,TAP,Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Gene ID: 110454

UniProt: P05533

Pathways: Sensory Perception of Sound, Activated T Cell Proliferation