TACR3 antibody (AA 151-250)

Catalog No. ABIN725735

Product Details anti-TACR3 Antibody

Target: TACR3 (Tachykinin Receptor 3 (TACR3))

Binding Specificity: AA 151-250

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NKR

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TACR3 antibody (ABIN725735)

Obata, Shimo, Okui, Matsumoto, Takada, Takabatake, Kunisada, Ibaragi, Yoshioka, Kishimoto, Nagatsuka, Sasaki: "Role of Neurokinin 3 Receptor Signaling in Oral Squamous Cell Carcinoma." in: Anticancer research, Vol. 37, Issue 11, pp. 6119-6123, (2017) (PubMed).

Obata, Shimo, Okui, Matsumoto, Takada, Takabatake, Kunisada, Ibaragi, Nagatsuka, Sasaki: "Tachykinin Receptor 3 Distribution in Human Oral Squamous Cell Carcinoma." in: Anticancer research, Vol. 36, Issue 12, pp. 6335-6341, (2016) (PubMed).

Target Details for TACR3

Target: TACR3 (Tachykinin Receptor 3 (TACR3))

Alternative Name: Neurokinin B receptor (TACR3 Products)

Synonyms: HH11 antibody, NK-3R antibody, NK3R antibody, NKR antibody, TAC3RL antibody, Nk3r antibody, Nkr antibody, Tac3r antibody, Nmkr antibody, tachykinin receptor 3 antibody, neuromedin-K receptor antibody, TACR3 antibody, LOC100544805 antibody, Tacr3 antibody

Background:

Synonyms: NKR, HH11, NK3R, NK-3R, TAC3RL, Neuromedin-K receptor, NK-3 receptor, Neurokinin B receptor, Tachykinin receptor 3, TACR3, TAC3R

Background: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

Gene ID: 6870

UniProt: P29371

Pathways: Feeding Behaviour