TACR3 antibody (AA 151-250)

Catalog No. ABIN725735

There are 2+ publications for this product available. The Rabbit Polyclonal anti-TACR3 antibody is suitable to detect TACR3 in samples from Human. It has been validated for IHC (p), FACS, IF (cc), IF (p) and IHC (fro).

Quick Overview for TACR3 antibody (AA 151-250) (ABIN725735)

Target: TACR3 (Tachykinin Receptor 3 (TACR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TACR3 Antibody

Binding Specificity: AA 151-250

Purpose: Neurokin B receptor Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NKR

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TACR3 antibody (ABIN725735)

Obata, Shimo, Okui, Matsumoto, Takada, Takabatake, Kunisada, Ibaragi, Yoshioka, Kishimoto, Nagatsuka, Sasaki: "Role of Neurokinin 3 Receptor Signaling in Oral Squamous Cell Carcinoma." in: Anticancer research, Vol. 37, Issue 11, pp. 6119-6123, (2017) (PubMed).

Obata, Shimo, Okui, Matsumoto, Takada, Takabatake, Kunisada, Ibaragi, Nagatsuka, Sasaki: "Tachykinin Receptor 3 Distribution in Human Oral Squamous Cell Carcinoma." in: Anticancer research, Vol. 36, Issue 12, pp. 6335-6341, (2016) (PubMed).

Target Details for TACR3

Target: TACR3 (Tachykinin Receptor 3 (TACR3))

Alternative Name: Neurokinin B receptor

Background:

Synonyms: NKR, HH11, NK3R, NK-3R, TAC3RL, Neuromedin-K receptor, NK-3 receptor, Neurokinin B receptor, Tachykinin receptor 3, TACR3, TAC3R

Background: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

Gene ID: 6870

UniProt: P29371

Pathways: Feeding Behaviour