IRS3 antibody (AA 261-360) (Biotin)

Catalog No. ABIN726007

This Rabbit Polyclonal antibody specifically detects IRS3 in WB, IHC (fro) and IHC (p). It exhibits reactivity toward Rat.

Quick Overview for IRS3 antibody (AA 261-360) (Biotin) (ABIN726007)

Target: IRS3 (Insulin Receptor Substrate 3 (IRS3))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS3 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IRS3 Antibody (Biotin)

Binding Specificity: AA 261-360

Purpose: IRS3 Polyclonal Antibody, Biotin Conjugated

Cross-Reactivity: Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat IRS-3

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for IRS3

Target: IRS3 (Insulin Receptor Substrate 3 (IRS3))

Alternative Name: IRS-3

Background:

Synonyms: IRS1--Insulin receptor substrate-3, IRS3, IRS-3, IRS3.

Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.

Gene ID: 84021