IRS3 antibody (AA 261-360) (Cy3)

Catalog No. ABIN726008

The Rabbit Polyclonal anti-IRS3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect IRS3 in samples from Rat, Human, Mouse and Pig.

Quick Overview for IRS3 antibody (AA 261-360) (Cy3) (ABIN726008)

Target: IRS3 (Insulin Receptor Substrate 3 (IRS3))

Reactivity: Rat, Human, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS3 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-IRS3 Antibody (Cy3)

Binding Specificity: AA 261-360

Cross-Reactivity: Human, Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat IRS-3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IRS3

Target: IRS3 (Insulin Receptor Substrate 3 (IRS3))

Alternative Name: IRS-3

Background:

Synonyms: IRS1--Insulin receptor substrate-3, IRS3, IRS-3, IRS3.

Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.

Gene ID: 84021