ENPP2 antibody

Catalog No. ABIN7581209

This Goat Polyclonal antibody specifically detects ENPP2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ENPP2 antibody (ABIN7581209)

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ENPP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ENPP2 Antibody

Purpose: Goat polycolonal antibody targeting human Autotaxin (ATX)

Specificity: Anti-ATX antibody recognizes endogenous human ATX and is predicted to recognize rat, mouse, horse, and feline ATX based on amino acid conservation.

Purification: affinity purified

Immunogen: ATX peptide

Isotype: IgG

Application Details

Application Notes: WB – 1:1000, ELISA – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: Antibody is stable for up to 1 year at -20°C. Antibody is stable at 4°C for up to 60 days. Avoid repeated freeze/thaw cycles.

Target Details for ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Alternative Name: Autotaxin

Background: ATX, also known as ENPP2, cleaves choline from lysophosphatidylcholine forming lysophosphatidic acid (LPA), a potent mitogen that has been implicated in the pathophysiology of ovarian cancer. ATX has been demonstrated to increase cell motility, neovascularization, proliferation, and aggressiveness of tumors and is upregulated in numerous cancer lineages (non-small cell lung , glioma, mammary carcinoma, renal cell carcinoma, hepatocellular carcinoma). In addition, dysregulation of the ATX/LPA pathway is central to the pathophysiology of idiopathic pulmonary fibrosis, rheumatoid arthritis, and other inflammatory diseases.