Recombinant DLL4 (Demcizumab Biosimilar) antibody
Quick Overview for Recombinant DLL4 (Demcizumab Biosimilar) antibody (ABIN7675738)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Expression System
- CHO Cells
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Purpose
- Anti-DLL4 Reference Antibody (demcizumab)
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Sequence
- QVQLVQSGAE VKKPGASVKI SCKASGYSFT AYYIHWVKQA PGQGLEWIGY ISSYNGATNY NQKFKGRVTF TTDTSTSTAY MELRSLRSDD TAVYYCARDY DYDVGMDYWG QGTLVTVSSA STKGPSVFPL APCSRSTSES TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSNFGTQTY TCNVDHKPSN TKVDKTVERK CCVECPPCPA PPVAGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VQFNWYVDGV EVHNAKTKPR EEQFNSTFRV VSVLTVVHQD WLNGKEYKCK VSNKGLPAPI EKTISKTKGQ PREPQVYTLP PSREEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPMLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPG,DIVMTQSPDS LAVSLGERAT ISCRASESVD NYGISFMKWF QQKPGQPPKL LIYAASNQGS GVPDRFSGSG SGTDFTLTIS SLQAEDVAVY YCQQSKEVPW TFGGGTKVEI KRTVAAPSVF IFPPSDEQLK SGTASVVCLL NNFYPREAKV QWKVDNALQS GNSQESVTEQ DSKDSTYSLS STLTLSKADY EKHKVYACEV THQGLSSPVT KSFNRGEC
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Characteristics
- Anti-DLL4 Reference Antibody (demcizumab) is expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
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Purity
- >95 %
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Isotype
- IgG2SA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Therapeutic Agents by Target and Mechanism: DLL4 inhibitors
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 1 mg/mL
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Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
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Storage
- 4 °C,-80 °C
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Storage Comment
- +4°C,-80°C
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- DLL4 (Demcizumab Biosimilar)
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Target Type
- Biosimilar
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Molecular Weight
- 145.5 kDa
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UniProt
- Q9NR61
Target
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