Recombinant F12 (Garadacimab Biosimilar) antibody

Catalog No. ABIN7675873

This Human Monoclonal antibody specifically detects F12 (Garadacimab Biosimilar) in BLI, ELISA, FACS, Func and SPR. It exhibits reactivity toward Human.

Quick Overview for Recombinant F12 (Garadacimab Biosimilar) antibody (ABIN7675873)

Target: F12 (Garadacimab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This F12 (Garadacimab Biosimilar) antibody is un-conjugated

Application: Bio-Layer Interferometry (BLI), ELISA, Flow Cytometry (FACS), Functional Studies (Func), Surface Plasmon Resonance (SPR)

Product Details anti-F12 (Garadacimab Biosimilar) Antibody

Expression System: CHO Cells

Purpose: Anti-F12 / Factor XII Reference Antibody (garadacimab)

Sequence: EVQLLESGGG LVQPGGSLRL SCAASGFTFS KYIMQWVRQA PGKGLEWVSG IDIPTKGTVY ADSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCARAL PRSGYLISPH YYYYALDVWG QGTTVTVSSA STKGPSVFPL APCSRSTSES TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSSLGTKTY TCNVDHKPSN TKVDKRVESK YGPPCPPCPA PEFLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSQEDP EVQFNWYVDG VEVHNAKTKP REEQFNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKGLPSS IEKTISKAKG QPREPQVYTL PPSQEEMTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSRLT VDKSRWQEGN VFSCSVMHEA LHNHYTQKSL SLSLGK,QSVLTQPPSA SGTPGQRVTI SCSGSSSNIG RNYVYWYQQL PGTAPKLLIY SNNQRPSGVP DRFSGSKSGT SASLAISGLR SEDEADYYCA AWDASLRGVF GGGTKLTVLG QPKAAPSVTL FPPSSEELQA NKATLVCLIS DFYPGAVTVA WKADSSPVKA GVETTTPSKQ SNNKYAASSY LSLTPEQWKS HRSYSCQVTH EGSTVEKTVA PTECS

Characteristics: Anti-F12 / Factor XII Reference Antibody (garadacimab) is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa.

Purity: >95 %

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Therapeutic Agents by Target and Mechanism: F12 inhibitors, Factor XIIa inhibitors

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

Storage: 4 °C,-80 °C

Storage Comment: +4°C,-80°C

Target Details for F12 (Garadacimab Biosimilar)

Target: F12 (Garadacimab Biosimilar)

Target Type: Biosimilar

Molecular Weight: 145.5 kDa

UniProt: P00748