Recombinant IL-4RA (Dupilumab Biosimilar) antibody
Reactivity: Human
ELISA, FACS, BLI, Func, SPR
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
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- Target See all IL-4RA (Dupilumab Biosimilar) products
- IL-4RA (Dupilumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
-
Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
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Conjugate
- This IL-4RA (Dupilumab Biosimilar) antibody is un-conjugated
- Application
- ELISA, Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), Functional Studies (Func), Surface Plasmon Resonance (SPR)
- Purpose
- Anti-IL-4Ra / CD124 Reference Antibody (dupilumab)
- Sequence
- EVQLVESGGG LEQPGGSLRL SCAGSGFTFR DYAMTWVRQA PGKGLEWVSS ISGSGGNTYY ADSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCAKDR LSITIRPRYY GLDVWGQGTT VTVSSASTKG PSVFPLAPCS RSTSESTAAL GCLVKDYFPE PVTVSWNSGA LTSGVHTFPA VLQSSGLYSL SSVVTVPSSS LGTKTYTCNV DHKPSNTKVD KRVESKYGPP CPPCPAPEFL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSQEDPEVQF NWYVDGVEVH NAKTKPREEQ FNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KGLPSSIEKT ISKAKGQPRE PQVYTLPPSQ EEMTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSRLTVDKS RWQEGNVFSC SVMHEALHNH YTQKSLSLSL G,DIVMTQSPLS LPVTPGEPAS ISCRSSQSLL YSIGYNYLDW YLQKSGQSPQ LLIYLGSNRA SGVPDRFSGS GSGTDFTLKI SRVEAEDVGF YYCMQALQTP YTFGQGTKLE IKRTVAAPSV FIFPPSDEQL KSGTASVVCL LNNFYPREAK VQWKVDNALQ SGNSQESVTE QDSKDSTYSL SSTLTLSKAD YEKHKVYACE VTHQGLSSPV TKSFNRGEC
- Characteristics
- Anti-IL-4Ra / CD124 Reference Antibody (dupilumab) is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG4SP
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anti-IL-4RA (Dupilumab Biosimilar) antibody
Research Grade Reactivity: Human ELISA, FACS Host: Human Monoclonal unconjugated Recombinant Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Therapeutic Agents by Target and Mechanism: IL-4Ra inhibitors
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
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- Target
- IL-4RA (Dupilumab Biosimilar)
- Abstract
- IL-4RA (Dupilumab Biosimilar) Products
- Target Type
- Biosimilar
- Molecular Weight
- 145.5 kDa
- UniProt
- P24394
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