Recombinant IL-4RA (Dupilumab Biosimilar) antibody
This Mouse Monoclonal antibody specifically detects IL-4RA (Dupilumab Biosimilar) in FACS and in vivo. It exhibits reactivity toward Human.
Catalog No. ABIN7795142
$1,115.38
Plus shipping costs $50.00
5 mg
Shipping to:
United States
Delivery in 6 to 9 Business Days
Quick Overview for Recombinant IL-4RA (Dupilumab Biosimilar) antibody (ABIN7795142)
Target
IL-4RA (Dupilumab Biosimilar)
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
This IL-4RA (Dupilumab Biosimilar) antibody is un-conjugated
Application
Flow Cytometry (FACS), In vivo Studies (in vivo)
Grade
Research Grade
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Expression System
- Mammalian cells
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Purpose
- Dupilumab Biosimilar, Endotoxin 0.05 EU/mg
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Characteristics
- What is dupilumab biosimilar research grade? Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis. Dupilumab binds to the alpha subunit of the interleukin-4 receptor (IL-4Ra), making it a receptor antagonist. Through blockade of IL-4Ra, dupilumab modulates signaling of both the interleukin 4 and interleukin 13 pathways. Dupilumab biosimilar uses the same protein sequences as the therapeutic antibody dupilumab.
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Endotoxin Level
- Less than 0.5 EU/mg of protein as determined by LAL method
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Immunogen
- Human IL4R alpha
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anti-IL-4RA (Dupilumab Biosimilar) antibody
Research Grade Reactivity: Human FACS, ELISA Host: Human Monoclonal unconjugated Recombinant Antibody
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- IL-4RA (Dupilumab Biosimilar)
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Alternative Name
- Dupilumab Biosimilar
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Target Type
- Biosimilar
Target
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