Recombinant TNFRSF10B (Conatumumab Biosimilar) antibody
The Human Monoclonal anti-TNFRSF10B (Conatumumab Biosimilar) antibody (ABIN7675660) specifically detects TNFRSF10B (Conatumumab Biosimilar) in ELISA, BLI, FACS, Func and SPR.
The antibody is reactive with Human samples.
Catalog No. ABIN7675660
$346.15
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Quick Overview for Recombinant TNFRSF10B (Conatumumab Biosimilar) antibody (ABIN7675660)
Target
TNFRSF10B (Conatumumab Biosimilar)
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Human
Clonality
Monoclonal
Conjugate
This TNFRSF10B (Conatumumab Biosimilar) antibody is un-conjugated
Application
ELISA, Bio-Layer Interferometry (BLI), Flow Cytometry (FACS), Functional Studies (Func), Surface Plasmon Resonance (SPR)
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Expression System
- CHO Cells
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Purpose
- Anti-TNFRSF10B / TRAILR2 / CD262 Reference Antibody (conatumumab)
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Sequence
- QVQLQESGPG LVKPSQTLSL TCTVSGGSIS SGDYFWSWIR QLPGKGLEWI GHIHNSGTTY YNPSLKSRVT ISVDTSKKQF SLRLSSVTAA DTAVYYCARD RGGDYYYGMD VWGQGTTVTV SSASTKGPSV FPLAPSSKST SGGTAALGCL VKDYFPEPVT VSWNSGALTS GVHTFPAVLQ SSGLYSLSSV VTVPSSSLGT QTYICNVNHK PSNTKVDKRV EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR EEMTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK,EIVLTQSPGT LSLSPGERAT LSCRASQGIS RSYLAWYQQK PGQAPSLLIY GASSRATGIP DRFSGSGSGT DFTLTISRLE PEDFAVYYCQ QFGSSPWTFG QGTKVEIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC
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Characteristics
- Anti-TNFRSF10B / TRAILR2 / CD262 Reference Antibody (conatumumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 144.96 kDa.
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Purity
- >95 %
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Therapeutic Agents by Target and Mechanism: DR5 agonist
Conditions: Cancer
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 1 mg/mL
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Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
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Storage
- 4 °C,-80 °C
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Storage Comment
- +4°C,-80°C
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- TNFRSF10B (Conatumumab Biosimilar)
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Target Type
- Biosimilar
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Background
- Synonyms: TNFRSF10B (tumor necrosis factor receptor superfamily member 10B, TRAIL-R2, TRAILR2, TR-2, CD262
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Molecular Weight
- 144.96 kDa
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UniProt
- O14763
Target
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