Recombinant TNFSF11 (Denosumab Biosimilar) antibody
Reactivity: Human
FACS, BLI, ELISA, Func, SPR
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
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- Target See all TNFSF11 (Denosumab Biosimilar) products
- TNFSF11 (Denosumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
-
Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
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Conjugate
- This TNFSF11 (Denosumab Biosimilar) antibody is un-conjugated
- Application
- Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), ELISA, Functional Studies (Func), Surface Plasmon Resonance (SPR)
- Purpose
- Anti-TNFSF11 / RANKL / CD254 Reference Antibody (denosumab)
- Sequence
- EVQLLESGGG LVQPGGSLRL SCAASGFTFS SYAMSWVRQA PGKGLEWVSG ITGSGGSTYY ADSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCAKDP GTTVIMSWFD PWGQGTLVTV SSASTKGPSV FPLAPCSRST SESTAALGCL VKDYFPEPVT VSWNSGALTS GVHTFPAVLQ SSGLYSLSSV VTVPSSNFGT QTYTCNVDHK PSNTKVDKTV ERKCCVECPP CPAPPVAGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVQFNWYV DGVEVHNAKT KPREEQFNST FRVVSVLTVV HQDWLNGKEY KCKVSNKGLP APIEKTISKT KGQPREPQVY TLPPSREEMT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPMLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGK,EIVLTQSPGT LSLSPGERAT LSCRASQSVR GRYLAWYQQK PGQAPRLLIY GASSRATGIP DRFSGSGSGT DFTLTISRLE PEDFAVFYCQ QYGSSPRTFG QGTKVEIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC
- Characteristics
- Anti-TNFSF11 / RANKL / CD254 Reference Antibody (denosumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG1
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Therapeutic Agents by Target and Mechanism: RANKL inhibitors
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
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- Target
- TNFSF11 (Denosumab Biosimilar)
- Abstract
- TNFSF11 (Denosumab Biosimilar) Products
- Target Type
- Biosimilar
- Molecular Weight
- 145.5 kDa
- UniProt
- O14788
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