GFRA1 antibody (AA 351-429) (Biotin)

Catalog No. ABIN726232

This Rabbit Polyclonal antibody specifically detects GFRA1 in WB, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for GFRA1 antibody (AA 351-429) (Biotin) (ABIN726232)

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRA1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GFRA1 Antibody (Biotin)

Binding Specificity: AA 351-429

Purpose: GDNFRA Polyclonal Antibody, Biotin Conjugated

Specificity: This antibody exhibits a secondary cross-reactivity towards Exonuclease-1 due to a 60 % contigueous sequence similarity over the immunogen range.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GFR Alpha-1

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GFRA1

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Alternative Name: GDNFRA

Background:

Synonyms: GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1, GDNF family receptor alpha-1, GDNF receptor alpha-1, GDNFR-alpha-1, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1, GFRA1

Background: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).

Gene ID: 2674

UniProt: P56159