PAX5 antibody (PE)

Catalog No. ABIN7595381

This Rat Monoclonal antibody specifically detects PAX5 in ICFC. It exhibits reactivity toward Human and Mouse.

Quick Overview for PAX5 antibody (PE) (ABIN7595381)

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This PAX5 antibody is conjugated to PE

Application: Intracellular Flow Cytometry (ICFC)

Clone: 1H9

Product Details anti-PAX5 Antibody (PE)

Purpose: Anti-PAX5 PE

Specificity: The rat monoclonal antibody 1H9 recognizes transcription factor PAX5 (intracellular antigen).

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: GST-tagged recombinant mouse PAX5

Isotype: IgG2a kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background: PAX5 is a transcription factor expressed in hematopoietic cells of B cell line, and partially also in the nervous system. It is important for B cell development and differentiation, but its expression must finally be be suppressed to enable plasma cell maturation. PAX5 thus affects the balance between B cell proliferation and antibody production. Its overexpression is associated with many lymphomas.

Gene ID: 5079

UniProt: Q02548