EPO antibody (AA 28-193)

Catalog No. ABIN7596017

This anti-EPO antibody is a Mouse Monoclonal antibody detecting EPO in WB and ELISA. Suitable for Human.

Quick Overview for EPO antibody (AA 28-193) (ABIN7596017)

Target: EPO (Erythropoietin (EPO))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPO antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: AT1C12

Product Details anti-EPO Antibody

Binding Specificity: AA 28-193

Purpose: Human Erythropoietin/EPO antibody

Purification: protein-A affinity chromatography

Immunogen: Recombinant human Erythropoietin (28-193aa) purified from insect cell

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for EPO

Target: EPO (Erythropoietin (EPO))

Alternative Name: Erythropoietin/EPO

Target Type: Hormone

Background: EPO, also known as erythropoietin, is a glycoprotein hormone in the type I cytokine family and is related to thrombopoietin. Its three N-glycosylation sites, four alpha helices, and N- to C-terminal disulfide bond are conserved across species. It is primarily produced in the kidney by a population of fibroblast-like cortical interstitial cells adjacent to the proximal tubules. This protein can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and anti-apoptotic functions in several tissue types.

NCBI Accession: NP_000790

Pathways: JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity