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TLR7 antibody (AA 451-500)

This anti-TLR7 antibody is a Mouse Monoclonal antibody detecting TLR7 in WB, ELISA and FACS. Suitable for Human.
Catalog No. ABIN7596035

Quick Overview for TLR7 antibody (AA 451-500) (ABIN7596035)

Target

See all TLR7 Antibodies
TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivity

  • 95
  • 45
  • 9
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 93
  • 19
Mouse

Clonality

  • 81
  • 30
  • 1
Monoclonal

Conjugate

  • 67
  • 8
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
This TLR7 antibody is un-conjugated

Application

  • 64
  • 48
  • 33
  • 17
  • 14
  • 11
  • 8
  • 7
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone

4F4
  • Binding Specificity

    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-500

    Purpose

    Human TLR7 antibody

    Purification

    protein-A affinity chromatography

    Immunogen

    Recombinant human TLR7 (451-500aa) purified from E. coli.

    Isotype

    IgG1 kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target

    TLR7 (Toll-Like Receptor 7 (TLR7))

    Alternative Name

    TLR7

    Background

    TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity byrecognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine richrepeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptormolecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7, 8 genes are located on the sexchromosome X. hTLR7 may play an important role in detecting and combating viral infections.

    NCBI Accession

    NP_057646

    Pathways

    TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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