COTL1 antibody (AA 1-142)
Quick Overview for COTL1 antibody (AA 1-142) (ABIN7596079)
Target
See all COTL1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-142
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Purpose
- Human Coactosin-like Protein 1/COTL1 antibody
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Purification
- Purified
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Immunogen
- Recombinant human COTL1 (1-142aa) purified from E. coli
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Isotype
- IgG2b kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing cycles
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- COTL1 (Coactosin-Like Protein)
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Alternative Name
- Coactosin-like Protein 1/COTL1
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Background
- COTL1 (coactosin-like 1), also known as CLP, is a 142 amino acid cytoplasmic and cytoskeletal proteinthat belongs to the actin-binding proteins ADF family and coactosin subfamily. COTL1 is first identified inslime mold and is found at highest levels in kidney, placenta, lung and peripheral blood leukocytes. COTL1 isone of many proteins that participate in regulation of Actin's cytoskeleton through a calcium dependent mechanism,but has not been shown to have a direct effect on Actin depolymerization.
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NCBI Accession
- NP_066972
Target
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